| Veno-occlusive disease in hematopoietic stem cell transplantation recipients. | |
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MedLine Citation:
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PMID: 23022934 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Veno-occlusive disease (VOD) is a potentially fatal complication of hematopoietic stem cell transplantation that affects the liver, as well as other organs. Although mild cases resolve on their own, severe cases of VOD carry a high mortality rate. The diagnosis usually is clinically based, with nonspecific signs such as weight gain, ascites, hepatomegaly, right upper quadrant abdominal pain, and elevated serum bilirubin. Although studies are ongoing, no U.S. Food and Drug Administration-approved treatments for VOD exist to date. Therefore, supportive care is a critical part of the treatment plan. Oncology nurses should be familiar with the risk factors and clinical signs of VOD so that patients can be monitored closely for its occurrence. Accurate and timely recognition of VOD is crucial for appropriate treatment. |
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Authors:
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Elisabeth C Sosa |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical journal of oncology nursing Volume: 16 ISSN: 1538-067X ISO Abbreviation: Clin J Oncol Nurs Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9705336 Medline TA: Clin J Oncol Nurs Country: United States |
Other Details:
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Languages: eng Pagination: 507-13 Citation Subset: N |
Affiliation:
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Florida Hospital in Orlando. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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