| VenaFlow plus Lovenox vs VenaFlow plus aspirin for thromboembolic disease prophylaxis in total knee arthroplasty. | |
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MedLine Citation:
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PMID: 16950076 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two hundred seventy-five patients undergoing unilateral total knee arthroplasty were prospectively randomized to receive spinal epidural anesthesia (SEA), a VenaFlow calf compression device, and enoxaparin (group A) or SEA, VenaFlow, and aspirin (group B). Aspirin was started on the day of surgery, whereas enoxaparin was started 48 hours after surgery. Anticoagulants were continued for 4 weeks after surgery. All patients had an in-hospital ultrasound screening test on postoperative days 3 to 5 and a second follow-up ultrasound 4 to 6 weeks after surgery. The overall deep venous thrombosis rates in groups A and B were 14.1% and 17.8% (P = not significant), respectively. When used in combination with pneumatic compression devices and SEA, enoxaparin was not superior to aspirin in preventing deep venous thrombosis after total knee arthroplasty. |
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Authors:
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Geoffrey H Westrich; Friedrich Bottner; Russell E Windsor; Richard S Laskin; Steven B Haas; Thomas P Sculco |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of arthroplasty Volume: 21 ISSN: 0883-5403 ISO Abbreviation: J Arthroplasty Publication Date: 2006 Sep |
Date Detail:
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Created Date: 2006-09-04 Completed Date: 2006-12-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8703515 Medline TA: J Arthroplasty Country: United States |
Other Details:
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Languages: eng Pagination: 139-43 Citation Subset: IM |
Affiliation:
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Hospital for Special Surgery-Weill Medical College, Cornell University, New York City, New York, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Anesthesia, Spinal / methods Arthroplasty, Replacement, Knee / adverse effects* Aspirin / therapeutic use* Combined Modality Therapy Enoxaparin / therapeutic use* Female Fibrinolytic Agents / therapeutic use* Humans Intermittent Pneumatic Compression Devices* Male Middle Aged Postoperative Care / methods* Thromboembolism / etiology, prevention & control* Ultrasonography Venous Thrombosis / etiology, prevention & control* |
| Chemical | |
Reg. No./Substance:
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0/Enoxaparin; 0/Fibrinolytic Agents; 50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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