Document Detail

Vegetarian diets and blood pressure among white subjects: results from the Adventist Health Study-2 (AHS-2).
MedLine Citation:
PMID:  22230619     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Previous work studying vegetarians has often found that they have lower blood pressure (BP). Reasons may include their lower BMI and higher intake levels of fruit and vegetables. Here we seek to extend this evidence in a geographically diverse population containing vegans, lacto-ovo vegetarians and omnivores.
DESIGN: Data are analysed from a calibration sub-study of the Adventist Health Study-2 (AHS-2) cohort who attended clinics and provided validated FFQ. Criteria were established for vegan, lacto-ovo vegetarian, partial vegetarian and omnivorous dietary patterns.
SETTING: Clinics were conducted at churches across the USA and Canada. Dietary data were gathered by mailed questionnaire.
SUBJECTS: Five hundred white subjects representing the AHS-2 cohort.
RESULTS: Covariate-adjusted regression analyses demonstrated that the vegan vegetarians had lower systolic and diastolic BP (mmHg) than omnivorous Adventists (β = -6.8, P < 0.05 and β = -6.9, P < 0.001). Findings for lacto-ovo vegetarians (β = -9.1, P < 0.001 and β = -5.8, P < 0.001) were similar. The vegetarians (mainly the vegans) were also less likely to be using antihypertensive medications. Defining hypertension as systolic BP > 139 mmHg or diastolic BP > 89 mmHg or use of antihypertensive medications, the odds ratio of hypertension compared with omnivores was 0.37 (95 % CI 0.19, 0.74), 0.57 (95 % CI 0.36, 0.92) and 0.92 (95 % CI 0.50, 1.70), respectively, for vegans, lacto-ovo vegetarians and partial vegetarians. Effects were reduced after adjustment for BMI.
CONCLUSIONS: We conclude from this relatively large study that vegetarians, especially vegans, with otherwise diverse characteristics but stable diets, do have lower systolic and diastolic BP and less hypertension than omnivores. This is only partly due to their lower body mass.
Betty J Pettersen; Ramtin Anousheh; Jing Fan; Karen Jaceldo-Siegl; Gary E Fraser
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural     Date:  2012-01-10
Journal Detail:
Title:  Public health nutrition     Volume:  15     ISSN:  1475-2727     ISO Abbreviation:  Public Health Nutr     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-14     Completed Date:  2012-12-21     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  9808463     Medline TA:  Public Health Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  1909-16     Citation Subset:  IM    
Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, 24785 Stewart Street, Loma Linda, CA 92350, USA.
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MeSH Terms
Antihypertensive Agents / therapeutic use
Blood Pressure / physiology*
Body Mass Index
Canada / epidemiology
Cohort Studies
Diet / statistics & numerical data*
Diet, Vegetarian*
European Continental Ancestry Group / statistics & numerical data*
Food Habits / physiology*
Hypertension / drug therapy,  epidemiology*
Middle Aged
Odds Ratio
United States / epidemiology
Grant Support
5R01 CA094594/CA/NCI NIH HHS; R01 CA094594/CA/NCI NIH HHS
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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