Document Detail

Vasospastic angina after chemotherapy by with carboplatin and etoposide in a patient with lung cancer.
MedLine Citation:
PMID:  8741246     Owner:  NLM     Status:  MEDLINE    
We report here a case of vasospastic angina following the administration of Carboplatin (CBDCA) and Etoposide (VP-16) in a patient with small cell lung carcinoma. Although these drugs are commonly used to treat small cell lung carcinoma, there has been no previous report of vasospastic angina in a patient without a history of heart disease. Therefore, we should be aware of the possibility that vasospastic angina may develop even in a patient without any history of heart disease. While calcium antagonist and isosorbide dinitrate are generally helpful for preventing vasospastic angina, these drugs could not completely suppress vasospastic angina in this case.
S Yano; K Shimada
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  60     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-11-19     Completed Date:  1996-11-19     Revised Date:  2006-04-24    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  185-8     Citation Subset:  IM    
Department of Pulmonary Medicine, Shiga Prefectural Medical Center, Japan.
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MeSH Terms
Angina Pectoris / chemically induced*
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Carboplatin / adverse effects
Carcinoma, Small Cell / complications,  drug therapy*
Coronary Vasospasm / chemically induced*
Etoposide / adverse effects
Lung Neoplasms / complications,  drug therapy*
Reg. No./Substance:
33419-42-0/Etoposide; 41575-94-4/Carboplatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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