Document Detail


Vasospasms are characteristic in cases with eclampsia/preeclampsia and HELLP syndrome: proposal of an angiospastic syndrome of pregnancy.
MedLine Citation:
PMID:  11372766     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We attempted to prove the occurrence of generalized vasospasms in cases with eclampsia/preeclampsia and HELLP syndrome and to suggest the existence of an angiospastic syndrome of pregnancy. Sixteen cases with severe preeclampsia were evaluated. Among them, three cases were complicated by eclampsia and one case with HELLP syndrome. Cranial magnetic resonance angiography (MRA) was performed in 15 cases, and celiac angiography was performed in one case. Vasospasms were observed in 12 cases (75.0%), including all cases involving eclampsia and HELLP syndrome, and cerebral infarction was observed in one case. Typical vasospasms were found by MRA in the middle and posterior cerebral arteries with peripheral ischemic changes in cases with severe preeclampsia and eclampsia. Vasospasms of the hepatic arteries were observed by celiac angiography in a case with HELLP syndrome. Vasospasms are characteristic for patients with eclampsia/preeclampsia and HELLP syndrome, and the existence of an angiospastic syndrome of pregnancy is proposed.
Authors:
T Kobayashi; N Tokunaga; H Isoda; N Kanayama; T Terao
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Seminars in thrombosis and hemostasis     Volume:  27     ISSN:  0094-6176     ISO Abbreviation:  Semin. Thromb. Hemost.     Publication Date:  2001  
Date Detail:
Created Date:  2001-05-24     Completed Date:  2001-12-07     Revised Date:  2006-03-07    
Medline Journal Info:
Nlm Unique ID:  0431155     Medline TA:  Semin Thromb Hemost     Country:  United States    
Other Details:
Languages:  eng     Pagination:  131-5     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Shizuoka, Japan. tkoba@hama-med.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
HELLP Syndrome / etiology,  physiopathology*
Humans
Magnetic Resonance Angiography
Pre-Eclampsia / etiology,  physiopathology*
Pregnancy
Spasm / complications,  physiopathology*
Vasoconstriction

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