Document Detail


Vasopressor agents: old and new components.
MedLine Citation:
PMID:  15166834     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: In settings of cardiac arrest, reestablishing vital organ perfusion plays an important role in initial CPR. As a pharmacologic intervention, vasopressor agents aim to improve aortic diastolic pressure and, consequently, coronary and cerebral perfusion pressures. RECENT FINDINGS: Historically, adrenergic agonists such as epinephrine have been suggested for routine use in CPR. However, epinephrine's efficacy is controversial because of its unfavorable inotropic and chronotropic action. This has prompted research into the use of alternative pressor agents with more promising hemodynamic features; these include selective alpha 2-adrenergic agonists and other nonadrenergic vasoconstrictors such as vasopressin. SUMMARY: In this article, the main traditional and novel adrenergic and nonadrenergic vasopressor drugs are reviewed.
Authors:
Lei Huang; Wanchun Tang
Related Documents :
23702694 - Cerebrovascular pressure reactivity and cerebral oxygen regulation after severe head in...
9485244 - Retrograde coronary perfusion: effects on iatrogenic edema and diastolic properties.
1725364 - Nicardipine inhibits the endothelin-1-induced constriction of systemic capacitance and ...
19108154 - Peripheral actions of hexamethonium in relation to the decreasing effects of repeated d...
3289894 - Effect of baroreceptor denervation on the inhibition of renin release by vasopressin.
19960134 - Successful treatment of hypertension accounts for improvements in markers of diastolic ...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in critical care     Volume:  10     ISSN:  1070-5295     ISO Abbreviation:  Curr Opin Crit Care     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-05-28     Completed Date:  2004-10-06     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9504454     Medline TA:  Curr Opin Crit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  183-7     Citation Subset:  IM    
Affiliation:
The Institute of Critical Care Medicine, Palm Springs, California 92262, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adrenergic Agents / classification,  pharmacology,  therapeutic use*
Cardiopulmonary Resuscitation / methods*
Critical Care / methods
Heart Arrest / drug therapy*,  therapy
Humans
Vasoconstrictor Agents / classification,  pharmacology,  therapeutic use*
Chemical
Reg. No./Substance:
0/Adrenergic Agents; 0/Vasoconstrictor Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Fungal infection in the very low birthweight infant.
Next Document:  Combination of active compression decompression cardiopulmonary resuscitation and the inspiratory im...