| Vasopressin response to lactate infusion in normals and patients with panic disorder. | |
| | |
MedLine Citation:
|
PMID: 3609849 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Infusions of sodium lactate evoke panic symptoms in patients with panic disorder but not in normal subjects. Although plasma vasopressin (AVP) is known to rise in response to other forms of stress, its response during this maneuver has not previously been reported. We measured plasma AVP in double-blind infusions of sodium lactate in 5 normal subjects, 6 patients with panic disorder, and, again in 4 patients after chronic alprazolam. In all groups administered lactate, AVP rose significantly above baseline values (p less than 0.05) though no change was seen in a control group of patients during D5NS infusion. No difference in AVP response to lactate was apparent between untreated patients (who experienced panic) and normals or chronically treated patients (who had minimal symptoms). Thus, the presence of panic symptoms induced by lactate is insufficient to provoke an abnormal pattern of AVP release. |
| | |
Authors:
|
D B Carr; S M Fishman; N W Kasting; D V Sheehan |
Related Documents
:
|
7925339 - Post-dural puncture headache: a comparison of the sprotte and yale needles in urologica... 17044579 - Unusual visual symptoms in a patient with bilateral vertebral artery dissection: a case... 20647239 - Confusional migraine is an adult as well as a childhood disease. 19282179 - Asymmetric dimethylarginine and nitric oxide levels in migraine during the interictal p... 19946119 - Head-to-head comparison of real-time three-dimensional transthoracic echocardiography w... 16162259 - A single-fibre emg study of neuromuscular transmission in migraine patients. 8648009 - Increased intestinal permeability in bronchial asthma. 20525739 - Salivary chemokine levels in patients with primary sjogren's syndrome. 15790409 - Hand-held echocardiography: added value in clinical cardiological assessment. |
Publication Detail:
|
Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
|
Title: Functional neurology Volume: 1 ISSN: 0393-5264 ISO Abbreviation: Funct. Neurol. Publication Date: 1986 Apr-Jun |
Date Detail:
|
Created Date: 1987-08-28 Completed Date: 1987-08-28 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8707746 Medline TA: Funct Neurol Country: ITALY |
Other Details:
|
Languages: eng Pagination: 123-7 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Alprazolam / therapeutic use Anxiety Disorders / drug therapy, physiopathology* Fear / drug effects* Female Humans Lactates / pharmacology* Lactic Acid Male Middle Aged Panic / drug effects* Vasopressins / blood* |
| Chemical | |
Reg. No./Substance:
|
0/Lactates; 11000-17-2/Vasopressins; 28981-97-7/Alprazolam; 50-21-5/Lactic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Classic and common migraine suggestive clinical evidence of two separate entities.
Next Document: Akinetic mutism and locked-in syndrome: the functional-anatomical basis for their differentiation.