Document Detail


Vasopressin release induced by hypothension is blunted in patients with diabetic autonomic neuropathy.
MedLine Citation:
PMID:  20370555     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The response of arginin-vasopressin (AVP) to baroreceptor activation (tilt testing) was investigated in patients with diabetic autonomic neuropathy (DAN). The present data show that hypothension induced by upright position showed a slight increase of AVP in patients with DAN in comparison with normal subjects and diabetic patients without DAN. These findings suggest that the blunted AVP response to hypothension may be due to lesions of afferent autonomic pathways present in DAN and plays a role in the pathogenesis of postural hypothension.
Authors:
M Iovino; V Triggiani; B Licchelli; E Tafaro; V Giagulli; C Sabbà; F Resta; S V Sciannimanico; R Panza; E Guastamacchia
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Publication Detail:
Type:  Journal Article     Date:  2010-04-07
Journal Detail:
Title:  Immunopharmacology and immunotoxicology     Volume:  33     ISSN:  1532-2513     ISO Abbreviation:  Immunopharmacol Immunotoxicol     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8800150     Medline TA:  Immunopharmacol Immunotoxicol     Country:  England    
Other Details:
Languages:  eng     Pagination:  224-6     Citation Subset:  IM    
Affiliation:
Department of Endocrinology, General Hospital of Eboli, ASL SA, Piazza Scuola Medica Salernitana, 84025 Eboli, Italy.
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