| Vasopressin for the management of catecholamine-resistant anaphylactic shock. | |
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MedLine Citation:
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PMID: 18830525 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Severe anaesthetic anaphylaxis is relatively uncommon. Oxygen, fluids and epinephrine are considered to be the mainstay for treatment of cardiovascular collapse and current guidelines for the management of anaphylaxis list only epinephrine as a vasopressor to use in the event of a cardiovascular collapse. Recently, evidence has emerged in the support of the use of vasopressin in cardiopulmonary resuscitation; it is also recommended for the treatment of ventricular fibrillation, septic shock and post-cardiopulmonary bypass distribution shock. Currently, there is no algorithm or guideline for the management of anaphylaxis that include the use of vasopressin. We report a 24-year-old woman who developed severe anaphylactic shock at induction of anaesthesia while undergoing laparoscopic cholecystectomy. Circulation shock was refractory to epinephrine and high doses of pure alpha-agonist phenylephrine and norepinephrine. Single intravenous dose of two units of vasopressin re-established normal circulation and blood pressure. |
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Authors:
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A M Hussain; B Yousuf; M A Khan; F H Khan; F A Khan |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Singapore medical journal Volume: 49 ISSN: 0037-5675 ISO Abbreviation: Singapore Med J Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-10-02 Completed Date: 2009-07-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404516 Medline TA: Singapore Med J Country: Singapore |
Other Details:
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Languages: eng Pagination: e225-8 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology, Aga Khan University Hospital, Stadium Road, PO Box 3500, Karachi 74800, Pakistan. aziza.mohammad@aku.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Algorithms Anaphylaxis / chemically induced*, drug therapy* Blood Pressure Catecholamines / therapeutic use* Cholecystectomy / methods Drug Resistance Epinephrine / pharmacology Female Humans Norepinephrine / pharmacology Phenylephrine / pharmacology Treatment Outcome Vasoconstrictor Agents / therapeutic use* Vasopressins / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Catecholamines; 0/Vasoconstrictor Agents; 11000-17-2/Vasopressins; 51-41-2/Norepinephrine; 51-43-4/Epinephrine; 59-42-7/Phenylephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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