Document Detail


Vasodilators in Acute Heart Failure: Review of the Latest Studies.
MedLine Citation:
PMID:  24855585     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Vasodilators play an important role in the management of acute heart failure, particularly when increased afterload is the precipitating cause of decompensation. The time-honored approach to afterload reduction has been largely focused on use of intravenous nitrovasodilators and, when properly dosed, this class of agents does provide substantial symptom relief for patients with acute hypertensive heart failure. Despite this, nitrovasodilators have never been shown to diminish mortality or provide any post-discharge outcome benefit leading to an on-going search for viable and more effective alternatives. While no new vasodilators have been approved for use in acute heart failure since nesiritide more than a decade ago, a number of novel agents have been developed, with some showing significant promise in recent clinical trials. In this review, we summarize the latest study data as it relates to vasodilator therapy and provide a glimpse into the not too distant future state of acute heart failure care.
Authors:
Phillip D Levy; Said Laribi; Alexandre Mebazaa
Related Documents :
23645915 - Influenza-like illness in acute myocardial infarction patients during the winter wave o...
19808375 - Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remode...
7317315 - Type a behaviour, life-events and myocardial infarction: independent or related risk fa...
12208595 - Plasma concentrations of fibrinolytic factors in the subacute phase of myocardial infar...
18971785 - Plasma b-type natriuretic peptide in diagnosing inferior myocardial infarction with rig...
21316505 - Patterns of ventricular tachyarrhythmias associated with training, deconditioning and r...
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Current emergency and hospital medicine reports     Volume:  2     ISSN:  2167-4884     ISO Abbreviation:  Curr Emerg Hosp Med Rep     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-5-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101604815     Medline TA:  Curr Emerg Hosp Med Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  126-132     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Ras-Mediated Signal Transduction and Virulence in Human Pathogenic Fungi.
Next Document:  Durable bonds at the adhesive/dentin interface: an impossible mission or simply a moving target?