Document Detail

Vasodilators for heart failure--useful or useless?
MedLine Citation:
PMID:  3069208     Owner:  NLM     Status:  MEDLINE    
Vasodilators have gained widespread acceptance in the management of congestive heart failure. They produce prompt hemodynamic and clinical improvement in acute left ventricular failure, and in chronic congestive heart failure they also improve symptoms, functional capacity, and survival. This efficacy, however, is limited to those vasodilators which have venodilating ability, such as nitrates and angiotensin-converting enzyme inhibitors, when they are added to digitalis and diuretics in patients with moderate to severe heart failure. The utility of vasodilators without digitalis or diuretics requires further evaluation. The potential for vasodilators to prevent the development or progression of heart failure from latent to clinically overt disease is also being evaluated.
J A Franciosa
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cardiology     Volume:  75 Suppl 1     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1988  
Date Detail:
Created Date:  1989-04-27     Completed Date:  1989-04-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  110-7     Citation Subset:  IM    
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia.
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MeSH Terms
Angiotensin-Converting Enzyme Inhibitors / therapeutic use
Heart Failure / drug therapy*
Vasodilator Agents / therapeutic use*
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Vasodilator Agents

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