| Vasodilator therapy in acute myocardial infarction. | |
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MedLine Citation:
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PMID: 1042028 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the context of these studies, the evidence indicates that cardiac performance can improve significantly during vasodilator therapy in acute MI complicated by pump failure. Although the clinical course in uncomplicated patients is good, even without active therapeutic interventions, prognosis in patients with pump failure treated by standard methods (digitalis and diutetics) is discouraging. Hospital mortality approaches "40 per cent in patients with moderately depressed cardiac function and may reach as high as 100 per cent in patients with severe pump failure and/or cardiogenic shock." The evidence presented suggests that early and cautious vasodilator therapy may significantly alter this poor prognosis by its beneficial effects on both LV function and the determinants of myocardial oxygen consumption. |
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Authors:
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L Moskowitz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Heart & lung : the journal of critical care Volume: 4 ISSN: 0147-9563 ISO Abbreviation: Heart Lung Publication Date: 1975 Nov-Dec |
Date Detail:
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Created Date: 1976-02-13 Completed Date: 1976-02-13 Revised Date: 2006-08-28 |
Medline Journal Info:
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Nlm Unique ID: 0330057 Medline TA: Heart Lung Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 939-45 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Pressure Cardiac Output Heart Rate Humans Myocardial Infarction / drug therapy*, physiopathology Nitroprusside / therapeutic use Nursing Care Phentolamine / therapeutic use Vascular Resistance Vasodilator Agents / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Vasodilator Agents; 15078-28-1/Nitroprusside; 50-60-2/Phentolamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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