Document Detail

Vasodilator drugs in chronic obstructive airways disease.
MedLine Citation:
PMID:  2679615     Owner:  NLM     Status:  MEDLINE    
Short and long term administration of vasodilator drugs to patients with pulmonary artery hypertension (PAP) effects small falls of PAP and larger reductions of pulmonary vascular resistance due to increases of cardiac output. Side effects of systemic hypotension are sometimes troublesome. Improvement of survival has not yet been demonstrated. It is likely that any treatments capable of sustained clinical benefit in hypoxic cor pulmonale will have to arrest or reverse pathology in the airway and pulmonary vessel. There is no evidence that pulmonary vasodilator drugs will do this. Their clinical place is in doubt.
P Howard
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The European respiratory journal. Supplement     Volume:  7     ISSN:  0904-1850     ISO Abbreviation:  Eur Respir J Suppl     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-11-27     Completed Date:  1989-11-27     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8910681     Medline TA:  Eur Respir J Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  678s-681s     Citation Subset:  IM    
University Dept. of Medicine, Royal Hallamshire Hospital, Sheffield, UK.
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MeSH Terms
Hypertension, Pulmonary / drug therapy*,  etiology
Lung Diseases, Obstructive / complications*,  pathology
Vasodilator Agents / administration & dosage,  pharmacology,  therapeutic use*
Reg. No./Substance:
0/Vasodilator Agents

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