| VASOCONSTRICTOR ACTION OF TOLAZOLINE. | |
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MedLine Citation:
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PMID: 14126059 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In cats treated with reserpine and anaesthetized with pentobarbitone sodium the adrenergic blocking drug, tolazoline, caused a rise of arterial pressure which was inhibited by previous administration of phenoxybenzamine. Tolazoline increased the contractions of the isolated papillary muscles of normal cats but not of cats treated with reserpine. Intra-arterial injection of tolazoline into dogs treated with reserpine and anaesthetized with pentobarbitone sodium reduced the blood flow in the coeliac artery. It is considered that, following reserpine, tolazoline has a sympathomimetic vasoconstrictor action. |
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Authors:
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B G BENFEY; D R VARMA |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: British journal of pharmacology and chemotherapy Volume: 22 ISSN: 0366-0826 ISO Abbreviation: Br J Pharmacol Chemother Publication Date: 1964 Feb |
Date Detail:
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Created Date: 1964-07-01 Completed Date: 1996-12-01 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0154627 Medline TA: Br J Pharmacol Chemother Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 66-71 Citation Subset: OM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Circulation* Blood Pressure* Cats* Dogs* Papillary Muscles* Pharmacology* Research* Reserpine* Sympathomimetics* Tolazoline* |
| Chemical | |
Reg. No./Substance:
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0/Sympathomimetics; 50-55-5/Reserpine; 59-98-3/Tolazoline |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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