| Vasoactive intestinal polypeptide-like immunoreactivity in a human neuroblastoma cell line and the coexistence of other neuropeptide immunoreactivity in the cell line. | |
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MedLine Citation:
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PMID: 6164547 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The presence of VIP-like immunoreactivity in human neuroblastoma cell line NB-1 was demonstrated by radioimmunoassay of the crude cell extract and by immunocytochemical staining of the cells. Gel filtration profiles of VIP-like immunoreactivity in the cell extract measured by radioimmunoassays using three different region-specific antisera revealed that the immunoreactivity consists of a major molecular form corresponding to porcine VIP having 28 amino acid residues with at least two additional minor forms larger and smaller than the VIP. In addition to VIP-like immunoreactivity, the cell extract was shown to contain substance P-, neurotensin- and somatostatin-like immunoreactivity as well. |
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Authors:
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N Yanaihara; S Kobayashi; H Sato; C Yanaihara; M Sakagami; N Sakura; T Hashimoto; S Ishikawa; T Iwanaga; T Fujita |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Endocrinologia japonica Volume: 27 Suppl 1 ISSN: 0013-7219 ISO Abbreviation: Endocrinol. Jpn. Publication Date: 1980 Dec |
Date Detail:
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Created Date: 1981-07-20 Completed Date: 1981-07-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376546 Medline TA: Endocrinol Jpn Country: JAPAN |
Other Details:
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Languages: eng Pagination: 37-42 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Line Female Gastrointestinal Hormones / metabolism* Humans Neuroblastoma / analysis* Neurotensin / analysis Somatostatin / analysis Substance P / analysis Swine Vasoactive Intestinal Peptide / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Gastrointestinal Hormones; 33507-63-0/Substance P; 37221-79-7/Vasoactive Intestinal Peptide; 39379-15-2/Neurotensin; 51110-01-1/Somatostatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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