Document Detail

Vasculogenesis and angiogenesis in the IUGR placenta.
MedLine Citation:
PMID:  18482617     Owner:  NLM     Status:  MEDLINE    
Placenta vascular formation is important for fetal growth and development. Proper development of the placenta ensures the exchange of oxygen/nutrients and blood flow necessary for fetal growth. In this chapter, we will discuss the processes of vasculogenesis, angiogenesis, and pseudovasculogenesis during placental development and in pregnancies complicated by intrauterine growth restriction. Some of the factors controlling these processes include oxygen, the VEGF family of growth factors, and their receptors. Disruption in the balance of these controlling factors may explain the vascular malformations seen in pregnancies complicated by intrauterine growth restriction.
Juan A Arroyo; Virginia D Winn
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in perinatology     Volume:  32     ISSN:  0146-0005     ISO Abbreviation:  Semin. Perinatol.     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-16     Completed Date:  2008-09-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801132     Medline TA:  Semin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  172-7     Citation Subset:  IM    
Divisions of Maternal-Fetal Medicine and Basic Reproductive Biology, Department of Obstetrics and Gynecology, University of Colorado and Health Sciences Center, Aurora, CO 80045, USA.
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MeSH Terms
Chorionic Villi / physiology*
Fetal Growth Retardation / etiology*,  physiopathology
Growth Substances / physiology
Neovascularization, Pathologic / physiopathology*
Placenta / blood supply*,  pathology
Reg. No./Substance:
0/Growth Substances

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