Document Detail


Vasculitis of the temporal arteries in the young.
MedLine Citation:
PMID:  18538831     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Temporal artery vasculitis (TAV) in patients younger than 50 years is extremely rare. A case of TAV in an 18-year-old man is described here, followed by a literature review regarding cases of all types of vasculitic involvement of the temporal arteries in the young. METHODS: Review of the English literature on vasculitis involving the temporal arteries in young patients, based on a PubMed search. RESULTS: Less than 40 cases of vasculitic involvement of temporal arteries in the young have been described. TAV in the young may be divided into 3 groups: juvenile temporal arteritis, a localized eosinophilic arteritis confined to the temporal arteries, seems unique to this age group. Fifteen patients with juvenile temporal arteritis were described. Other vasculitides, such as polyarteritis nodosa, Churg-Strauss syndrome, and thrombangiitis obliterans may involve the temporal arteries in young patients. The literature search revealed 12 such cases. The least common group is arteritis in young patients, histologically resembling elderly type temporal arteritis, featuring 5 cases. In addition, other conditions such as Kimura disease and angiolymphoid hyperplasia with eosinophilia may resemble temporal arteritis in the young. CONCLUSIONS: TAV in the young is rare and differs from the classical temporal arteritis of older adults. There is an apparent overlap among several vasculitic conditions involving the temporal arteries in the young, and histological distinction may be difficult at times. The final diagnosis of the different conditions causing TAV in the young is based on a combination of clinical findings, relevant laboratory data, imaging studies, and histological findings.
Authors:
Gideon Nesher; Shirly Oren; Graciela Lijovetzky; Ronit Nesher
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2008-06-09
Journal Detail:
Title:  Seminars in arthritis and rheumatism     Volume:  39     ISSN:  1532-866X     ISO Abbreviation:  Semin. Arthritis Rheum.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-02     Completed Date:  2009-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1306053     Medline TA:  Semin Arthritis Rheum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  96-107     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Rheumatology Service, Shaare-Zedek Medical Center, Jerusalem, Israel. nesher@inter.net.il
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Female
Giant Cell Arteritis / diagnosis*,  physiopathology,  therapy
Humans
Male
Temporal Arteries / pathology*,  physiopathology
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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