Document Detail

Vasculitis Presenting with Myocardial Infarction, Stroke, and Aortitis in a Middle-aged Man.
MedLine Citation:
PMID:  20685065     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Vasculitis may cause inflammation in any single or group of blood vessels. Traditionally, giant cell arteritis involves the extracranial branches of the carotid, and Takayasu arteritis affects the aorta and its major branches. These diseases are quite rare, but have the potential to be fatal.
OBJECTIVES: We describe the spectrum of overlap between these two historically distinct diseases, and use a case of a man with arteritis involving his carotid and vertebral vessels, aorta, and coronary arteries to illustrate this. We posit that large-vessel vasculitis should be considered in the differential for young and middle-aged patients presenting with multiple vascular events.
CASE REPORT: Over a 2-month period, a 46-year-old man presented on four separate occasions to the Emergency Department. Each time, he was diagnosed with a vascular event. His first two visits were for myocardial infarction and unstable angina, his third visit was for a cerebrovascular event, and his fourth visit was for aortitis. He was not diagnosed with the underlying vasculitic process until his last visit. He ultimately succumbed to non-aneurysmal aortic rupture from his aortitis.
CONCLUSIONS: In middle-aged persons with multiple vascular events, an underlying inflammatory process should be considered. These diseases are rare, but they are treatable; and missed diagnoses can be catastrophic.
Gregory Wheeler; Jesse Kropf; Rebecca Jeanmonod
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Publication Detail:
Type:  Journal Article     Date:  2010-08-04
Journal Detail:
Title:  The Journal of emergency medicine     Volume:  43     ISSN:  0736-4679     ISO Abbreviation:  J Emerg Med     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8412174     Medline TA:  J Emerg Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  655-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
St. Luke's Hospital and Health Network, Bethlehem, Pennsylvania.
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