| Vasculitides associated with infections, immunization, and antimicrobial drugs. | |
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MedLine Citation:
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PMID: 7795045 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Many pathogenic microbes can induce a complex series of immunologic, endothelial-cell, and hemorheological activation cascades and dysfunctions and can cause interactions of various components of the vessel wall with formed and noncellular elements of the blood. These interactions can result in manifold vasculitides. This article reviews the pathogenetic, clinicopathologic, and therapeutic aspects of infection-related vasculitides; it includes a brief discussion of parasitic, drug-related, and immunization-associated vasculitides as well as of the infection-related features of vasculitides of the central nervous system, retinal vasculitides, ecthyma gangrenosum, and erythema nodosum. Viruses are mainly associated with small-vessel vasculitides, whereas bacterial infections affect vessels of all sizes, including the aorta. The vasculitides associated with fungal infection usually are characterized by erythema nodosum and involve large vessels. The search for microbes as causes of or contributors to vasculitides should continue. Infectious vasculitides may become increasingly important as the number of immunocompromised patients grows. |
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Authors:
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T Somer; S M Finegold |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 20 ISSN: 1058-4838 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 1995 Apr |
Date Detail:
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Created Date: 1995-07-28 Completed Date: 1995-07-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1010-36 Citation Subset: IM |
Affiliation:
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Third Department of Medicine, Helsinki University Central Hospital, Finland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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adverse effects Humans Immunization / adverse effects Infection / complications Retinal Vessels Vasculitis / classification, etiology* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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