| Vasculitides Throughout History and Their Clinical Treatment Today. | |
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MedLine Citation:
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PMID: 21904885 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Therapeutic management of the vasculitides is closely linked to modern rheumatologic advances, particularly as it relates to the discovery and first clinical use of glucocorticoids. These compounds were introduced in the late-1940s for the treatment of rheumatoid arthritis, but soon after, clinicians in Europe and the United States realized that they could have a significant positive impact in systemic vasculitides. However, once it was realized that glucocorticoid use was associated with a high degree of morbidity, the search for better immunosuppressive agents with similar efficacy but improved safety profiles was on. During the past several years, several agents have been utilized for the therapeutic management of systemic vasculitides, and the list keeps growing with the development of newer compounds that have retained efficacy but with a better safety profile. |
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Authors:
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Antonio Iglesias-Gamarra; Edgar Penaranda; Luis R Espinoza |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-9 |
Journal Detail:
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Title: Current rheumatology reports Volume: - ISSN: 1534-6307 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888970 Medline TA: Curr Rheumatol Rep Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Medicine, Division of Rheumatology, National University School of Medicine, Bogota, Colombia, iglesias.antonio1@gmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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