Document Detail


Vasculature of the mouse, rat, and rabbit testis-epididymis.
MedLine Citation:
PMID:  7158609     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The arrangement of blood vessels serving the testis-epididymis vas investigated microscopically in the mouse, rat, and rabbit. Blood vessels were visualized by infusing liquid silicone rubber into the vessels and subsequently clearing the surrounding tissue. Comprehensive illustrations of the vasculature were prepared from three-dimensional examinations. Arterial and venous vessels serving the testis-epididymis follow similar routes in all three species. However, the arrangements and characteristics of the blood vessels demonstrate dramatic species differences. For example, arteries within the testes have tight coils in the mouse and artery-artery anastomoses in the rat. Veins form vascular pathways that connect the testis and efferent ductules in all three species but also form a connection between the testis and cauda epididymidis in the rabbit only. Testosterone concentrations were determined in blood obtained by micropuncture of selected testis-epididymal veins. The measurements establish that the highest levels of testosterone are found in testicular surface veins. Also, vas deferential veins of the rabbit had significant amounts of testosterone. Studies of the blood-vessel volumes suggested that the volumes of arteries and veins in the testis are similar, whereas venous volumes exceed arterial volumes in all of the other organs examined. The studies provide comprehensive information about the architecture and physiology of blood vessels serving the testis-epididymis in the mouse, rat, and rabbit. Each species exhibits diversity in the vasculature and testosterone content of the veins. Veins connecting the testis to the efferent ductules and cauda epididymidis may provide for the preferential delivery of testicular secretions to androgen-dependent organs before the secretions are metabolized or diluted in the systemic blood.
Authors:
C Chubb; C Desjardins
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of anatomy     Volume:  165     ISSN:  0002-9106     ISO Abbreviation:  Am. J. Anat.     Publication Date:  1982 Dec 
Date Detail:
Created Date:  1983-03-11     Completed Date:  1983-03-11     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0376312     Medline TA:  Am J Anat     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  357-72     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Arteries / anatomy & histology
Blood Volume
Epididymis / blood supply*
Ligation
Male
Mice / anatomy & histology*
Mice, Inbred Strains
Rabbits / anatomy & histology*
Rats / anatomy & histology*
Rats, Inbred Strains
Testis / blood supply*
Testosterone / blood
Veins / anatomy & histology
Grant Support
ID/Acronym/Agency:
AG-00958/AG/NIA NIH HHS; HD-05501/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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