Document Detail


Vascularization of the placenta and the sub-placental myometrium: feasibility and reproducibility of a three-dimensional power Doppler ultrasound quantification technique. A pilot study.
MedLine Citation:
PMID:  20476879     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To assess the feasibility of placental and myometrial vascularization quantification using 3D power Doppler ultrasonography.
METHODS: 3D standardized acquisition was performed in the mid part of the utero-placental unit, once, in 38 patients undergoing normal pregnancies between 15 and 39 weeks. Vascularization parameters (VI, FI, and VFI) of placentae and myometrium were measured. Intra and inter-observer, as well as inter-acquisition reproducibility were evaluated.
RESULTS: Intra-class Correlation Coefficient of vascularization measurements were at least 0.94 for intra-observer, 0.92 for inter-observer, and 0.56 for inter-acquisition reproducibility. There was no significant difference for placental measurements for VI, FI and VFI between the second trimester and the third trimester pregnancies. Concerning the myometrium, we observed no significant difference between second and third trimester for FI. However, VI (28.090 vs. 19.374) and VFI (17.691 vs. 11.336) was significantly lower in the third trimester (p < 0.01).
CONCLUSION: 3D quantification of placental and myometrial vascular parameters is feasible with a high intra and inter-observer reproducibility. Evaluating a potential myometrial vascular impairment appears to be as relevant as studying the placenta alone and might be of great clinical interest. We believe that this technique should therefore be evaluated in clinical observational studies.
Authors:
Olivier Morel; Gilles Grangé; Jeanne Fresson; Jean P Schaaps; Jean M Foidart; Dominique Cabrol; Vassilis Tsatsaris
Related Documents :
2929699 - Determination of pentamidine transfer in the in vitro perfused human cotyledon with hig...
8547169 - Placental 11 beta-hydroxysteroid dehydrogenase and the programming of hypertension.
2850989 - The human placental bed: histology, immunohistochemistry and pathology.
1334939 - Malignant placental site trophoblastic tumor associated with placental abruption, fetal...
7873949 - Predictors of ratio of placental weight to fetal weight in multiethnic community.
20164029 - Expression of vegf receptors vefgr-1 and vegfr-2, angiopoietin receptors tie-1 and tie-...
24722709 - Adenomyosis in pregnancy mimicking morbidly adherent placenta.
14973179 - Nephron endowment and filtration surface area in the kidney after growth restriction of...
1426319 - The effects of spontaneous luteinizing hormone surges on superovulatory cycles.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-05-17
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  24     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  284-90     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Maternity of Nancy, University of Nancy I, Nancy, France. olivier.morel17@gmail.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  TAR syndrome and esophagial atresia: a concomitant or variant condition?
Next Document:  Concerns for decreased foetal movements in uncomplicated pregnancies--increased risk of foetal growt...