Document Detail


Vascular response in the femoropopliteal segment after implantation of an ePTFE balloon-expandable endovascular graft: an intravascular ultrasound study.
MedLine Citation:
PMID:  10883958     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To use intravascular ultrasound (IVUS) to document changes in vascular dimensions after placement of a balloon-expandable endograft. METHODS: Thirteen patients (9 men; mean age 62 years, range 47-75) treated with an investigational polytetrafluoroethylene endograft for obstructive disease of the femoropopliteal segment were studied with IVUS immediately after endograft implantation and at follow-up. Corresponding IVUS cross sections were analyzed for changes in lumen, vessel, and plaque areas seen inside the endograft, in the anastomotic segment, and in the remote arterial segment. RESULTS: A mean 6-month (range 1.5-9) follow-up was completed in 12 patients. Matched IVUS cross sections derived from within the endograft (n = 12) and at the endograft edges (n = 23) showed no change in lumen area (LA) in 17, reduction in 11, and dilatation in 7. Median changes within the endograft (+3%) were not significant (p = 0.28) and no neointima was found. Cross sections obtained at the anastomotic segment revealed a significant increase in LA (85%, p < 0.001), which was associated with a significant increase in both vessel area (VA) (42%, p < 0.001) and plaque area (PLA) (15%, p = 0.003) area. In the remote arterial segment, the change in LA was minimal (6%, p = 0.07), as were changes in the VA (9%, p = 0.04) and PLA (10%, p = 0.07). CONCLUSIONS: Following endograft placement, luminal changes within the endograft, at the endograft edges, and at the remote arterial segments were minimal. Intimal hyperplasia was not observed in the endograft. The distinct LA increase at the anastomotic segments was determined by the extent of VA and PLA change.
Authors:
M R van Sambeek; T Hagenaars; E J Gussenhoven; T C Leertouwer; A van der Lugt; M T Hoedt; H van Urk
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists     Volume:  7     ISSN:  1526-6028     ISO Abbreviation:  J. Endovasc. Ther.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-10-18     Completed Date:  2000-11-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100896915     Medline TA:  J Endovasc Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  204-12     Citation Subset:  IM    
Affiliation:
Department of Vascular Surgery, University Hospital, Rotterdam-Dijkzigt and Erasmus University, The Netherlands. vansambeek@hlkd.azr.nl
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MeSH Terms
Descriptor/Qualifier:
Aged
Angiography
Arterial Occlusive Diseases / radiography,  surgery*,  ultrasonography
Balloon Dilatation / instrumentation
Biocompatible Materials
Blood Vessel Prosthesis*
Blood Vessel Prosthesis Implantation / instrumentation*
Female
Femoral Artery* / radiography,  surgery,  ultrasonography
Humans
Male
Middle Aged
Polytetrafluoroethylene*
Popliteal Artery* / radiography,  surgery,  ultrasonography
Postoperative Period
Prosthesis Design
Retrospective Studies
Ultrasonography, Interventional*
Chemical
Reg. No./Substance:
0/Biocompatible Materials; 9002-84-0/Polytetrafluoroethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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