| Vascular perfusion of reproductive organs in pony mares and heifers during sedation with detomidine or xylazine. | |
| | |
MedLine Citation:
|
PMID: 19119960 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To assess the vascular effects of detomidine and xylazine in pony mares and heifers, respectively, as determined in a major artery and by extent of vascular perfusion of reproductive organs. ANIMALS: 10 pony mares and 10 Holstein heifers. PROCEDURES: Pony mares were assigned to receive physiologic saline (0.9% NaCl) solution (n = 5) or detomidine (3.0 mg/mare, IV; 5). Heifers were assigned to receive saline solution (5) or xylazine (14 mg/heifer, IM; 5). Color Doppler ultrasonographic examinations were performed immediately before and 10 minutes after administration of saline solution or sedative. In spectral Doppler mode, a spectral graph of blood flow velocities during a cardiac cycle was obtained at the internal iliac artery and at the ovarian pedicle. In color-flow mode, color signals of blood flow in vessels of the corpus luteum and endometrium were assessed. RESULTS: Systemic effects of sedation in the 2 species were evident as a decrease in heart rate; increase in duration of systole, diastole, or both; decrease in volume of blood flow; and decrease in velocity of blood flow within the internal iliac artery. However, an effect of sedatives on local vascular perfusion in the ovaries and endometrium was not detected. CONCLUSIONS AND CLINICAL RELEVANCE: Sedation with detomidine in pony mares and xylazine in heifers did not affect vascular perfusion in reproductive organs. These sedatives can be used in experimental and clinical color Doppler evaluations of vascular perfusion of the corpus luteum and endometrium. |
| | |
Authors:
|
Reno R Araujo; O J Ginther |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: American journal of veterinary research Volume: 70 ISSN: 0002-9645 ISO Abbreviation: Am. J. Vet. Res. Publication Date: 2009 Jan |
Date Detail:
|
Created Date: 2009-01-05 Completed Date: 2009-03-05 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0375011 Medline TA: Am J Vet Res Country: United States |
Other Details:
|
Languages: eng Pagination: 141-8 Citation Subset: IM |
Affiliation:
|
Eutheria Foundation, 4343 Garfoot Rd, Cross Plains, WI 53528, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenergic alpha-Agonists
/
pharmacology* Animals Blood Flow Velocity / physiology Blood Pressure / physiology Cattle / physiology* Corpus Luteum / blood supply*, drug effects, ultrasonography Endometrium / blood supply*, drug effects, ultrasonography Female Heart Rate / physiology Horses / physiology* Iliac Artery / ultrasonography Imidazoles / pharmacology* Random Allocation Ultrasonography, Doppler, Color / veterinary Xylazine / pharmacology* |
| Chemical | |
Reg. No./Substance:
|
0/Adrenergic alpha-Agonists; 0/Imidazoles; 7361-61-7/Xylazine; 76631-46-4/detomidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Development of an intramuscular xenograft model of canine osteosarcoma in mice for evaluation of the...
Next Document: Methods and microbial risks associated with composting of animal carcasses in the United States.