Document Detail

Vascular graft infection: the role of indium scanning.
MedLine Citation:
PMID:  2680609     Owner:  NLM     Status:  MEDLINE    
Infection of a prosthetic graft is one of the most feared complications of vascular surgery. The difficulties of accurate, objective diagnosis are well recognised. We have used III Indium labelled white blood cell scans (InWBC) in two groups: 9 control patients who underwent uncomplicated aortic aneurysm surgery, and 23 patients with suspected graft sepsis. In the control group there was one positive scan in a patient with an inflammatory aneurysm. In the suspected sepsis group, 11 patients subsequently has proven graft sepsis. Nine were correctly predicted by Indium scanning. Ten of 12 patients who did not have proven graft sepsis had negative scans. There was a total of 5 inflammatory aneurysms in the control and suspected sepsis groups, of whom two had positive scans. False positive scans were not present in the early postoperative period i patients without inflammatory aneurysms. In our experience Indium labelled WBC scanning for suspected graft sepsis has a accuracy of 83% a negative predictive value of 83% and a positive predictive value of 82%. These results suggest that Indium white cell labelling techniques which do not involve substantial cross-labelling of platelets are the best objective methods of establishing the presence or absence of graft sepsis.
D T Reilly; M J Grigg; D A Cunningham; E J Thomas; A O Mansfield
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of vascular surgery     Volume:  3     ISSN:  0950-821X     ISO Abbreviation:  Eur J Vasc Surg     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1989-12-06     Completed Date:  1989-12-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8709440     Medline TA:  Eur J Vasc Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  393-7     Citation Subset:  IM    
Department of Vascular Surgery St Mary's Hospital, Paddington, London U.K.
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MeSH Terms
Aorta / surgery
Aortic Aneurysm / surgery
Blood Vessel Prosthesis*
Femoral Artery / surgery
Iliac Artery / surgery
Indium Radioisotopes / diagnostic use*
Infection / etiology,  radionuclide imaging*
Leg / blood supply
Postoperative Complications / radionuclide imaging*
Predictive Value of Tests
Sensitivity and Specificity
Reg. No./Substance:
0/Indium Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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