| Vascular graft infection: the role of indium scanning. | |
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MedLine Citation:
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PMID: 2680609 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Infection of a prosthetic graft is one of the most feared complications of vascular surgery. The difficulties of accurate, objective diagnosis are well recognised. We have used III Indium labelled white blood cell scans (InWBC) in two groups: 9 control patients who underwent uncomplicated aortic aneurysm surgery, and 23 patients with suspected graft sepsis. In the control group there was one positive scan in a patient with an inflammatory aneurysm. In the suspected sepsis group, 11 patients subsequently has proven graft sepsis. Nine were correctly predicted by Indium scanning. Ten of 12 patients who did not have proven graft sepsis had negative scans. There was a total of 5 inflammatory aneurysms in the control and suspected sepsis groups, of whom two had positive scans. False positive scans were not present in the early postoperative period i patients without inflammatory aneurysms. In our experience Indium labelled WBC scanning for suspected graft sepsis has a accuracy of 83% a negative predictive value of 83% and a positive predictive value of 82%. These results suggest that Indium white cell labelling techniques which do not involve substantial cross-labelling of platelets are the best objective methods of establishing the presence or absence of graft sepsis. |
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Authors:
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D T Reilly; M J Grigg; D A Cunningham; E J Thomas; A O Mansfield |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of vascular surgery Volume: 3 ISSN: 0950-821X ISO Abbreviation: Eur J Vasc Surg Publication Date: 1989 Oct |
Date Detail:
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Created Date: 1989-12-06 Completed Date: 1989-12-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8709440 Medline TA: Eur J Vasc Surg Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 393-7 Citation Subset: IM |
Affiliation:
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Department of Vascular Surgery St Mary's Hospital, Paddington, London U.K. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aorta
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surgery Aortic Aneurysm / surgery Blood Vessel Prosthesis* Femoral Artery / surgery Humans Iliac Artery / surgery Indium Radioisotopes / diagnostic use* Infection / etiology, radionuclide imaging* Leg / blood supply Leukocytes Postoperative Complications / radionuclide imaging* Predictive Value of Tests Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Indium Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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