| Vascular complications in patients with aldosterone producing adenoma in Japan: comparative study with essential hypertension. The Research Committee of Disorders of Adrenal Hormones in Japan. | |
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MedLine Citation:
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PMID: 7594226 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The incidence of vascular complications in 224 patients with aldosterone-producing adenoma (APA) which was proven on adrenal surgery, was compared to that in 224 sex- and age-matched patients with essential hypertension (EHT). The incidence of cerebral hemorrhage was significantly higher (p < 0.05) in the patients with APA when compared to the EHT group. On the other hand, the incidence of myocardial infarction and/or congestive heart failure in the APA group was lower, although this difference did not reach statistical significance. Diastolic blood pressure in the APA group was significantly higher (p < 0.001) in the EHT group. However, a significant difference in diastolic blood pressure was not detected between the APA groups with and without vascular complications, whereas in the EHT group diastolic blood pressure was significantly higher (p < 0.001) in cases with vascular complications as compared to those without complications. As a possible factor contributing to the higher incidence of cerebral hemorrhage in the APA group, proteinuria was suggested. It was recommended that patients with primary aldosteronism should undergo operation when localization of the APA is established. |
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Authors:
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R Takeda; T Matsubara; I Miyamori; H Hatakeyama; T Morise |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of endocrinological investigation Volume: 18 ISSN: 0391-4097 ISO Abbreviation: J. Endocrinol. Invest. Publication Date: 1995 May |
Date Detail:
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Created Date: 1995-11-30 Completed Date: 1995-11-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7806594 Medline TA: J Endocrinol Invest Country: ITALY |
Other Details:
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Languages: eng Pagination: 370-3 Citation Subset: IM |
Affiliation:
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Second Department of Internal Medicine, School of Medicine, Kanazawa University, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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complications*,
metabolism Adrenal Cortex Neoplasms / complications*, metabolism Adult Aged Female Humans Hyperaldosteronism / complications*, etiology, metabolism Hypertension / complications*, metabolism Japan Male Middle Aged Vascular Diseases / etiology*, metabolism |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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