Document Detail

Vascular brachytherapy after percutaneous transluminal angioplasty of superficial femoral arteries-Polish pilot group.
MedLine Citation:
PMID:  12479908     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The article presents the results of treatment with vascular brachytherapy (VBT) in superficial femoral arteries. This method aims to minimize frequency of restenosis after percutaneous transluminal angioplasty (PTA). METHOD: Treatment was carried out in 20 cases. The patients with severe stenoses or total occlusions verified in angiography were selected. In the group of 19 patients, two were women (the average age of the patients was 58.7 years). VBT was performed immediately after PTA. A 15-Gy dose, with high dose rate, was applied. The dose was calculated based on individually chosen distance from the internal surface of the artery wall, which varied from 2 to 3 mm. The mean observation time after treatment was 8 months. The shortest time was 1 month and the longest 14 months. At the end of the observation time, the control DSA angiography was performed on every patient. RESULTS: During the first 2 months, in three cases, an acute thrombosis in treated artery was observed. In the third month, one treated artery occluded. In the sixth month of observation, one case of acute thrombosis was observed. The rest of the patients were free of restenoses. CONCLUSIONS: (1) In superficial femoral arteries, a low value of ankle brachial pressure index (ABPI; below 0.4) is very probably responsible for acute thrombosis after PTA with or without stent implantation followed by VBT. (2) Diabetes, rest ischaemia before treatment, poor vessel status confirmed in angiography may also be responsible for acute thrombosis after VBT. (3) Anticoagulants or antiplatelet (ticlipidine) treatment must be ordered for 6 months after VBT in patients with implanted stents.
Piotr Walichiewicz; Jerzy Piecuch; Brygida Bialas; Witold Orkisz; Marek Fijalkowski; Leszek Miszczyk
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular radiation medicine     Volume:  3     ISSN:  1522-1865     ISO Abbreviation:  Cardiovasc. Radiat. Med.     Publication Date:    2002 Jan-Mar
Date Detail:
Created Date:  2002-12-13     Completed Date:  2003-04-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100888865     Medline TA:  Cardiovasc Radiat Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2-6     Citation Subset:  IM    
Center of Oncology, Institute, Al. Armii Krajowej 15, 44-101, Gliwice, Poland.
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MeSH Terms
Angioplasty, Balloon*
Arterial Occlusive Diseases / complications,  epidemiology,  therapy*
Blood Vessel Prosthesis Implantation
Dose-Response Relationship, Radiation
Femoral Artery / radiography,  surgery*
Gamma Rays / therapeutic use
Graft Occlusion, Vascular / epidemiology,  etiology,  therapy
Middle Aged
Pilot Projects
Risk Factors
Thrombosis / epidemiology,  etiology,  therapy
Tibial Arteries / radiography,  surgery
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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