Document Detail


Varix of the extra-hepatic portion of the fetal intra-abdominal umbilical vein: pathogenesis, prenatal sonographic diagnosis, and perinatal outcome
MedLine Citation:
PMID:  16498367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: Aim of the study was to investigate pathogenesis, diagnosis, and prognosis of the fetal intra-abdominal umbilical vein varix (FIUVV). METHODS: We reviewed all cases of FIUVV diagnosed in our hospital from August 1999 to December 2002. The umbilical vein was considered dilated when the measurement was above 2 standard deviation of the mean for gestational age. In all cases prenatal echocardiography and post-natal karyotype were performed. Our cases were also considered in the light of all the cases of FIUVV reported in literature. RESULTS: FIUVV was diagnosed in 5 cases between 22 and 37 weeks' gestation, among an unselected population of pregnant woman. Karyotype was normal in all cases; an apparently isolated septal ventricular defect was present in one patient. No obstetrical complications due to the presence of FIUVV (i.e. thrombosis) were associated. CONCLUSIONS: In our case series no obstetrical complications, and only one mild fetal anomaly were present. In literature an high association has been reported between the presence of FIUVV and fetal anomalies and/or obstetrical complications. Fetal echocardiography and detailed US study of fetal anatomy is needed to exclude associated anomalies. Karyotype should be offered only when other fetal anomalies are present. In presence of FIUVV, a close fetal monitoring by serial color Doppler and ultrasonographic examinations should be performed.
Authors:
G Volpe; L Resta; P Volpe; R Stefanelli; M Minervini; N Volpe; L Buonadonna; M Gentile
Publication Detail:
Type:  English Abstract; Journal Article; Review    
Journal Detail:
Title:  Minerva ginecologica     Volume:  58     ISSN:  0026-4784     ISO Abbreviation:  Minerva Ginecol     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-02-24     Completed Date:  2006-07-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0400731     Medline TA:  Minerva Ginecol     Country:  Italy    
Other Details:
Languages:  ita     Pagination:  17-23     Citation Subset:  IM    
Affiliation:
U.O.C. Ostetricia e Ginecologia, Dipartimento Materno-Infantile A.U.S.L. BA/04, P.O. Di Venere, Bari.
Vernacular Title:
La varice del tratto intra-addominale extra-epatico della vena ombelicale fetale: patogenesi, diagnosi ecografica prenatale ed outcome perinatale.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Fetal Diseases* / etiology,  ultrasonography
Humans
Pregnancy
Prognosis
Ultrasonography, Prenatal*
Umbilical Veins*
Varicose Veins* / etiology,  ultrasonography

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