| Various Patterns of Intracardiac Electrogram T-Wave Alternans Prior to Ventricular Tachyarrhythmias in Implantable Cardioverter Defibrillator Patients. | |
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MedLine Citation:
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PMID: 22342862 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: It has been reported that intracardiac electrogram T-wave alternans (IE-TWA) is greater prior to spontaneous ventricular tachyarrhythmia than for baseline recordings. OBJECTIVE: The aim of this study was to investigate IE-TWA just prior to ventricular tachyarrhythmia episodes and at baseline, and compare these with microvolt TWA (M-TWA) measured during exercise. METHODS: We analyzed right ventricular ring-can electrogram recordings just prior to ventricular tachyarrhythmia (VTA) episodes and compared T-wave pattern and degree of variation to baseline recordings from 3 patients (two with idiopathic ventricular fibrillation and one with hypertrophic cardiomyopathy) who were enrolled in the Japan Intracardiac Electrogram TWA study of ICD recipients (J-TWAICD). In a stable state, we measured the M-TWA of the surface electrocardiogram during treadmill exercise in these three patients. RESULTS: We found three different patterns of IE-TWA among these three ICD patients immediately prior to spontaneous VTAs. Case 1 had AB pattern of IE-TWA, case 2 ABC pattern, and case 3 non-specific pattern but great T-wave amplitude variations. These IE-TWA amplitudes and distribution of T amplitude difference are greater than baseline. Case 1 had a positive outcome in regards to the M-TWA determination, whereas cases 2 and 3 did not. CONCLUSIONS: We indicate different patterns of IE-TWA prior to spontaneous VTAs. The phenomena of IE-TWA correspond to outcomes of M-TWA measured during exercise in the surface electrocardiogram. |
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Authors:
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Takanori Ikeda; Satoru Yusu; Yasuhiro Yokoyama; |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-15 |
Journal Detail:
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Title: Heart rhythm : the official journal of the Heart Rhythm Society Volume: - ISSN: 1556-3871 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101200317 Medline TA: Heart Rhythm Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012. Published by Elsevier Inc. |
Affiliation:
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Department of Cardiovascular Medicine, Toho University Medical Center, Tokyo, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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