Document Detail

Various Patterns of Intracardiac Electrogram T-Wave Alternans Prior to Ventricular Tachyarrhythmias in Implantable Cardioverter Defibrillator Patients.
MedLine Citation:
PMID:  22342862     Owner:  NLM     Status:  Publisher    
BACKGROUND: It has been reported that intracardiac electrogram T-wave alternans (IE-TWA) is greater prior to spontaneous ventricular tachyarrhythmia than for baseline recordings. OBJECTIVE: The aim of this study was to investigate IE-TWA just prior to ventricular tachyarrhythmia episodes and at baseline, and compare these with microvolt TWA (M-TWA) measured during exercise. METHODS: We analyzed right ventricular ring-can electrogram recordings just prior to ventricular tachyarrhythmia (VTA) episodes and compared T-wave pattern and degree of variation to baseline recordings from 3 patients (two with idiopathic ventricular fibrillation and one with hypertrophic cardiomyopathy) who were enrolled in the Japan Intracardiac Electrogram TWA study of ICD recipients (J-TWAICD). In a stable state, we measured the M-TWA of the surface electrocardiogram during treadmill exercise in these three patients. RESULTS: We found three different patterns of IE-TWA among these three ICD patients immediately prior to spontaneous VTAs. Case 1 had AB pattern of IE-TWA, case 2 ABC pattern, and case 3 non-specific pattern but great T-wave amplitude variations. These IE-TWA amplitudes and distribution of T amplitude difference are greater than baseline. Case 1 had a positive outcome in regards to the M-TWA determination, whereas cases 2 and 3 did not. CONCLUSIONS: We indicate different patterns of IE-TWA prior to spontaneous VTAs. The phenomena of IE-TWA correspond to outcomes of M-TWA measured during exercise in the surface electrocardiogram.
Takanori Ikeda; Satoru Yusu; Yasuhiro Yokoyama;
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-15
Journal Detail:
Title:  Heart rhythm : the official journal of the Heart Rhythm Society     Volume:  -     ISSN:  1556-3871     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101200317     Medline TA:  Heart Rhythm     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Inc.
Department of Cardiovascular Medicine, Toho University Medical Center, Tokyo, Japan.
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