Document Detail

Varicose veins.
MedLine Citation:
PMID:  19450366     Owner:  NLM     Status:  In-Process    
INTRODUCTION: Varicose veins are caused by poorly functioning valves in the veins, and decreased elasticity of the vein wall, allowing pooling of blood within the veins, and their subsequent enlargement. Varicose veins affect up to 40% of adults, and are more common in obese people, and in women who have had more than two pregnancies. METHODS AND OBJECTIVES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments in adults with varicose veins? We searched: Medline, Embase, The Cochrane Library and other important databases up to May 2007 (BMJ Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
RESULTS: We found 27 systematic reviews, RCTs, or observational studies that met our inclusion criteria.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: compression stockings, endovenous laser, injection sclerotherapy, radiofrequency ablation, self-help (advice, avoidance of tight clothing, diet, elevation of legs, exercise), and surgery (avulsion, powered phlebectomy, stripping).
Paul Tisi
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Publication Detail:
Type:  Journal Article     Date:  2007-10-18
Journal Detail:
Title:  Clinical evidence     Volume:  2007     ISSN:  1752-8526     ISO Abbreviation:  Clin Evid (Online)     Publication Date:  2007  
Date Detail:
Created Date:  2009-05-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101294314     Medline TA:  Clin Evid (Online)     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Bedford Hospital, Bedford, UK.
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