Document Detail

Varicella zoster CNS vascular complications. A report of four cases and literature review.
MedLine Citation:
PMID:  24976200     Owner:  NLM     Status:  MEDLINE    
This study explored the neurologic vascular complications of varicella zoster virus (VZV). We describe four patients presenting at our institution with neurologic involvement by VZV. MR and MRA studies of the intracranial arterial circulation in the head were read by board-certified radiologists using standard clinical procedures. On MRI, three patients had acute infarcts and in two instances irregularities and narrowings of vessels were visible. Many of these complications are recognized to be due to a vasculopathy affecting small or large vessels and resulting in cerebral infarctions and rarely hemorrhages. The pattern of cerebral infarction and vascular abnormalities is not specific and resembles those of vasculitis/vasculopathy from other causes. The central nervous system (CNS) vascular complications of VZV should be considered in the patients with simultaneous primary or prior VZV infection whose imaging studies show cerebral infarction and/or vasculitic appearing intracranial arteries.
Francisco Chiang; Theeraphol Panyaping; Gustavo Tedesqui; Daniel Sossa; Claudia Costa Leite; Mauricio Castillo
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2014-06-17
Journal Detail:
Title:  The neuroradiology journal     Volume:  27     ISSN:  1971-4009     ISO Abbreviation:  Neuroradiol J     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-06-30     Completed Date:  2014-09-12     Revised Date:  2014-10-22    
Medline Journal Info:
Nlm Unique ID:  101295103     Medline TA:  Neuroradiol J     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  327-33     Citation Subset:  IM    
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MeSH Terms
Brain / pathology*
Cerebral Infarction / etiology*,  pathology*
Child, Preschool
Encephalitis, Varicella Zoster / complications*,  pathology*
Middle Aged

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