Document Detail


Varicella pneumonia during pregnancy. Treatment of two cases with acyclovir.
MedLine Citation:
PMID:  3276333     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pneumonia is a rare but serious complication of varicella during pregnancy. Maternal mortality has been reported to be 41% with fetal and neonatal mortality at 65%. Treatment has included respiratory support and prophylactic antibiotics. Acyclovir has been prescribed with the intent to decrease the impact of the infection. It was added to the treatment protocol of two cases of varicella pneumonia in pregnancy. Despite the high maternal and perinatal mortality both pairs of patients and infants survived. Acyclovir did not appear to adversely influence the fetus, and may have contributed to the survival of mother and child.
Authors:
S E Eder; J J Apuzzio; G Weiss
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  5     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1988 Jan 
Date Detail:
Created Date:  1988-03-15     Completed Date:  1988-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  16-8     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark 07103.
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MeSH Terms
Descriptor/Qualifier:
Acyclovir / therapeutic use*
Adolescent
Adult
Chickenpox / complications,  drug therapy*
Combined Modality Therapy
Drug Therapy, Combination
Female
Humans
Infant, Newborn
Pneumonia, Viral / drug therapy*,  etiology
Positive-Pressure Respiration
Pregnancy
Pregnancy Complications, Infectious / drug therapy*,  etiology
Chemical
Reg. No./Substance:
59277-89-3/Acyclovir

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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