Document Detail

Varicella myocarditis in an adult.
MedLine Citation:
PMID:  11119480     Owner:  NLM     Status:  MEDLINE    
A 24 year old male with varicella myocarditis was admitted with chest pain and fever up to 39 degrees C. The ECG showed J point and ST elevation in leads V2-V4, and inverted T waves in leads V5 and V6. Creatine kinase (CK) was raised to 435 U/l (CK-MB 36 U/l), troponin I was 63.4 microgram/l, and lactate dehydrogenase was 359 U/l, suggesting cardiac involvement of varicella infection. The left ventricle was dilated (58 mm) and left ventricular ejection fraction was globally reduced (ejection fraction 45%). Myocarditis was confirmed by endomyocardial biopsy. The patient was treated with specific varicella hyperimmunoglobulins, aciclovir, and a non-steroidal anti-inflammatory drug. During two months follow up the patient recovered completely. This case report is a reminder that a varicella infection can cause myocarditis in adults. Early diagnosis and appropriate treatment of this rare form of myocarditis may lead to complete recovery.
P Alter; W Grimm; B Maisch
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  85     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2000-12-26     Completed Date:  2001-03-15     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  E2     Citation Subset:  IM    
Department of Internal Medicine-Cardiology, Philipps-University of Marburg, Baldingerstrabetae, D-35033 Marburg/Lahn, Germany.
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MeSH Terms
Chickenpox / diagnosis*
Herpesvirus 3, Human / isolation & purification
Myocarditis / diagnosis*

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