| Varicella as a trigger of atypical haemolytic uraemic syndrome associated with complement dysfunction: two cases. | |
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MedLine Citation:
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PMID: 19376828 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report two cases of children who presented with haemolytic uraemic syndrome following varicella infection. One of them had a membrane cofactor protein mutation, and the other had anti-factor H antibodies. These observations show that infectious agents such as varicella-zoster virus may be the trigger of haemolytic uraemic syndrome in patients with complement dysregulation. |
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Authors:
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Theresa Kwon; Alexandre Belot; Bruno Ranchin; Véronique Baudouin; Véronique Fremeaux-Bacchi; Marie-Agnès Dragon-Durey; Pierre Cochat; Chantal Loirat |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-04-17 |
Journal Detail:
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Title: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Volume: 24 ISSN: 1460-2385 ISO Abbreviation: Nephrol. Dial. Transplant. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-08-18 Completed Date: 2009-12-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8706402 Medline TA: Nephrol Dial Transplant Country: England |
Other Details:
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Languages: eng Pagination: 2752-4 Citation Subset: IM |
Affiliation:
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Pediatric Nephrology Department, Hôpital Robert Debré, Université Paris, France. theresa.kwon@rdb.aphp.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antigens, CD46
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deficiency*,
genetics Autoantibodies / blood* Chickenpox / complications*, genetics, immunology* Child, Preschool Complement Factor H / antagonists & inhibitors*, immunology Female Hemolytic-Uremic Syndrome / etiology*, genetics, immunology* Heterozygote Humans Male Point Mutation Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD46; 0/Autoantibodies; 0/CD46 protein, human; 80295-65-4/Complement Factor H |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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