Document Detail


Variations of magnesium, iron, copper and zinc during the colonic wound healing process: experimental study on rabbits.
MedLine Citation:
PMID:  1425825     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The role of trace elements in the wound-healing process is still controversial. Their variations within a normal colonic wound healing have never been studied. An experimental study on rabbits was designed to study magnesium, iron, copper and zinc variations in blood, normal colonic walls and colonic anastomoses on each of the first 7 postoperative days. No major variations of Mg could be observed. Fe decreased in blood as well as in colonic walls and anastomoses. Cu increased in blood, whereas it decreased in colonic walls and anastomoses. Zn decreased in blood, whereas it increased in colonic walls without significant changes in anastomoses. The role of Fe seemed to be rather difficult to understand. Plasma mobilization seems to explain the local use of Zn, while early tissue release with further return in blood occurred for Cu. The importance of a well-balanced nutritional status is underlined to prevent and correct the variations of trace elements in the postoperative course.
Authors:
F Vaxman; S Olender; H Maldonado; S Randriamananjo; G Chalkiadakis; A Lambert; T Wittmann; P Volkmar; J F Grenier
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes     Volume:  24     ISSN:  0014-312X     ISO Abbreviation:  Eur Surg Res     Publication Date:  1992  
Date Detail:
Created Date:  1992-12-22     Completed Date:  1992-12-22     Revised Date:  2006-11-30    
Medline Journal Info:
Nlm Unique ID:  0174752     Medline TA:  Eur Surg Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  283-90     Citation Subset:  IM    
Affiliation:
INSERM U61, Chirurgie B, Hospices Civils, Strasbourg, France.
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MeSH Terms
Descriptor/Qualifier:
Anastomosis, Surgical
Animals
Colon / metabolism,  physiology*,  surgery
Male
Postoperative Period
Rabbits
Reference Values
Time Factors
Trace Elements / blood*,  metabolism
Wound Healing*
Chemical
Reg. No./Substance:
0/Trace Elements

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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