Document Detail

Variations in upper urinary tract outflow resistance. The effect of high and low obstruction of ureter.
MedLine Citation:
PMID:  4023648     Owner:  NLM     Status:  MEDLINE    
The upper urinary tract of the pig was subjected to acute standardized obstructions, size 10-F, 8-F and 6-F, in both the proximal and the distal part of the ureter. Each obstruction was followed by measurements of the renal pelvic pressure-flow relationship between 0 and 20 ml/ureter/min. The study showed that the mean baseline pressure in the renal pelvis changed due to the obstruction with an increase related to the degree of obstruction. When the flow was increased a pressure-flow relationship in essence similar to the normal pressure-flow relationship was revealed. Thus phase 1, which is the pressure-flow relationship at low flow rate with urine flowing into a relaxed ureter, was practically eliminated and phase 2 was shifted to the left. The linear pressure-flow relationship in phase 3 was preserved but there was tendency for higher increments with increasing degree of obstruction. Even in cases of severe obstruction both baseline measurements and perfusion pressure measurements showed results well within the normal accepted limits of renal pelvic pressure. It was furthermore shown that the overlap was smallest at the low flow rates between 0 and 2 ml/ureter/min. All degrees of distal obstruction had a lower pressure at flow rates below 10 ml/ureter/min than proximal obstruction, a pressure difference which could be attributed to the peristaltic activity of the ureter.(ABSTRACT TRUNCATED AT 250 WORDS)
J Mortensen; J C Djurhuus; J Frøkiaer; H P Tofft
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of urology and nephrology     Volume:  19     ISSN:  0036-5599     ISO Abbreviation:  Scand. J. Urol. Nephrol.     Publication Date:  1985  
Date Detail:
Created Date:  1985-09-16     Completed Date:  1985-09-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0114501     Medline TA:  Scand J Urol Nephrol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  37-43     Citation Subset:  IM    
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MeSH Terms
Kidney Pelvis / physiopathology
Ureter / physiopathology
Ureteral Obstruction / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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