Document Detail

Variations in fibrinolytic activity of human whole saliva.
MedLine Citation:
PMID:  8930580     Owner:  NLM     Status:  MEDLINE    
The physiological variations of fibrinolytic activity (FA) in saliva were investigated in a population of 149 healthy volunteers including 12 pregnant women. An increase in FA could be observed with increasing age. Marked variations were observed during daytime with a peak value early in the morning. Higher FA values were observed in males as compared with females in the 20-39 yr age group. A clear decrease in FA was observed during pregnancy. A significant correlation existed between FA and suspended epithelial cell concentration, which seemed responsible for most of the physiological FA variations. It was concluded that age, sex, pregnancy, and the time of the day are important for salivary FA and should be taken into account in any study on salivary FA related to physiological or pathological processes.
P Majerus; B Dalcette; M Hermans; M Pourtois; P Capel
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of oral sciences     Volume:  104     ISSN:  0909-8836     ISO Abbreviation:  Eur. J. Oral Sci.     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1997-02-25     Completed Date:  1997-02-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9504563     Medline TA:  Eur J Oral Sci     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  341-5     Citation Subset:  D; IM    
Laboratory of Stomatology, Free University of Brussels, Belgium.
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MeSH Terms
Age Factors
Case-Control Studies
Cell Count
Circadian Rhythm
Epithelial Cells
Fibrinogen / metabolism
Fibrinolysis* / physiology
Middle Aged
Saliva / cytology,  metabolism,  physiology*,  secretion
Secretory Rate
Sex Factors
Thrombin / metabolism
Tissue Plasminogen Activator / metabolism
Reg. No./Substance:
9001-32-5/Fibrinogen; EC; EC Plasminogen Activator

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