Document Detail

Variation in mortality and intraventricular haemorrhage in occupants of Pacific Rim nurseries.
MedLine Citation:
PMID:  12047689     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: A network of neonatal intensive care units in Pacific Rim countries was formed to compare infant risk factors, clinical practices, and outcomes for very low birthweight infants. METHODOLOGY: A multicentre, prospective study compared outcomes for infants born smaller than 1501 g or at less than 31 weeks gestation. RESULTS: Gestational age-specific survival and incidence of intracranial haemorrhage varied for infants born in these nurseries. We found differences in infant risk factors among the nurseries. There were also significant differences in the use of antenatal steroids, but similar rates for Caesarean section and surfactant treatment. The factor most predictive of neonatal death and severe intracranial abnormality was an elevated Clinical Risk Index for Babies (CRIB) score. Antenatal steroid treatment (>24 h prior to delivery) was associated with improved survival and decreased incidence of severe intracranial abnormalities. Antenatal steroid treatment for less than 24 h prior to delivery was not associated with improved survival. Caesarean delivery was associated with improved survival, but showed no benefit regarding the incidence of severe intracranial abnormality. CONCLUSIONS: Our Pacific Rim nursery network found differences in neonatal outcomes that correlated best with measures of neonatal risk at birth, antenatal steroid treatment, and Caesarean delivery. These data emphasize the importance of obstetric care to improve postnatal outcomes in premature infants, and highlight the usefulness of CRIB scores in these patients.
A Martinez; H W Taeusch; V Yu; K W Tan; C-Y Yeung; J-H Lu; H Nishida; N-Y Boo
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  38     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-06-05     Completed Date:  2002-09-09     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  235-40     Citation Subset:  IM    
Department of Pediatrics, University of California San Francisco, San Francisco, CA 94110, USA.
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MeSH Terms
Analysis of Variance
Cerebral Hemorrhage / diagnosis,  epidemiology,  mortality*
Gestational Age
Infant Mortality / trends*
Infant, Newborn
Infant, Very Low Birth Weight*
Intensive Care Units, Neonatal
Logistic Models
Multivariate Analysis
Pacific Islands / epidemiology
Prospective Studies
Risk Assessment
Risk Factors
Survival Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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