Document Detail

Variation in maximum inspiratory and expiratory pressure after application of inspiratory loads in patients with COPD.
MedLine Citation:
PMID:  2306965     Owner:  NLM     Status:  MEDLINE    
We studied eight men with chronic obstructive pulmonary disease (COPD) (age, 60.57 +/- 7.59 years; height, 162 +/- 10.43 cm; weight, 65 +/- 9.7 kg). Functional values of the sample were as follows: FEV1, 46 percent; FVC, 67 percent; PO2, 72.4 mm Hg; and pH, 7.41. We used a modification of the Nickerson and Keens method. Patients were required to perform 65 percent of maximal inspiratory pressure (MIP). We counted the time from the start of the test to exhaustion of the patient (TLIM). We measured basal MIP and maximal expiratory pressure (MEP) (TLC) at the TLIM and 10, 20, and 30 minutes and MIP was different from the basal value (MIP basal, 85.7 cm H2O; MIP 10 minutes, 79.1 cm H2O; MIP 20 minutes, 78.6 cm H2O; MIP 30 minutes, 79.6 cm H2O. The MEP was not different from the basal value. We concluded that in patients with COPD, MIP decreases significantly after inspiration through umbral inspiratory weight equal to 65 percent MIP and does not return to basal value for 30 minutes. The MEP does not change with respect to basal determination.
J Fiz; M Gallego; J Izquierdo; J Ruiz; J Roig; J Morera
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chest     Volume:  97     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-04-02     Completed Date:  1990-04-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  618-20     Citation Subset:  AIM; IM; S    
Servei de Pneumologia, Hospital Germans Trias i Pujol, Barcelona, Spain.
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MeSH Terms
Airway Obstruction / physiopathology
Lung Diseases, Obstructive / physiopathology*
Lung Volume Measurements
Middle Aged
Pulmonary Ventilation / physiology*
Residual Volume / physiology
Respiratory Mechanics / physiology*
Respiratory Muscles / physiology
Total Lung Capacity / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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