Document Detail

Variation in cortical density within the cortical shell of individuals across a range in densities and ages.
MedLine Citation:
PMID:  23445918     Owner:  NLM     Status:  In-Data-Review    
Objectives: The purpose of this study was to determine variability in cortical volumetric bone density (vBMD) from a single slice tibia image over a range of vBMD readings and ages. Methods: Males and females (N=80; aged 6-80) were randomly selected from a previous study. Cortical vBMD at the anterior, posterior, medial, and lateral regions as well as the endocortical, mid-cortical, and pericortical regions of the cortical shell were determined using pQCT. Results: Mean anterior ROI cortical vBMD (1111±11 mg/cm) was lower than the posterior and lateral ROIs (1169±7 mg/cm and 1151±9 mg/cm, respectively), (p<0.05). Individuals with lower overall cortical vBMD and younger individuals had greater vBMD variability within the shell (r=0.37, p=0.004). Difference between anterior and posterior regions was inversely associated with cortical vBMD and jump power (r=0.46, p=0.001). Endocortical vBMD (1080±6 mg/cm) was lower than the mid-cortical and pericortical regions (1152±5 mg/cm and 1147±5 mg/cm, respectively). Conclusions: Variability in cortical vBMD was higher among young individuals and those with lower overall cortical vBMD, while lowest in older individuals and men. The anterior ROI had lower mean cortical vBMD than posterior or lateral regions, and endocortical vBMD was lower than the mid- and pericortical regions.
L A Weidauer; T L Binkley; R Berry; B L Specker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of musculoskeletal & neuronal interactions     Volume:  13     ISSN:  1108-7161     ISO Abbreviation:  J Musculoskelet Neuronal Interact     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101084496     Medline TA:  J Musculoskelet Neuronal Interact     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  89-96     Citation Subset:  IM    
Ethel Austin Martin Program in Human Nutrition, South Dakota State University.
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