Document Detail

Variation in circulating immune complex levels with diet, exercise, and sleep: a comparison between normal controls and patients with systemic lupus erythematosus.
MedLine Citation:
PMID:  6895450     Owner:  NLM     Status:  MEDLINE    
Circulating immune complexes (CIC) were measured in 4 normal controls and 8 patients with systemic lupus erythematosus (SLE) by a polyethylene glycol precipitation (PEG) method during a 24-hour period. In all the normal controls levels fell during sleep and after drinking 1 pint (568 ml) of milk and rose before getting out of bed and after moderate exercise. There were also marked differences in the patterns of rise and fall of the CIC levels between the normal controls and patients with SLE. Insufficient account has been taken of these physiological influences in CIC levels in previous studies attempting to relate disease activity to quantitative levels.
D A Isenberg; A J Crisp; W J Morrow; D Newham; M L Snaith
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the rheumatic diseases     Volume:  40     ISSN:  0003-4967     ISO Abbreviation:  Ann. Rheum. Dis.     Publication Date:  1981 Oct 
Date Detail:
Created Date:  1982-01-28     Completed Date:  1982-01-28     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372355     Medline TA:  Ann Rheum Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  466-9     Citation Subset:  IM    
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MeSH Terms
Antigen-Antibody Complex / metabolism*
Circadian Rhythm
Lupus Erythematosus, Systemic / immunology*
Middle Aged
Physical Exertion*
Reg. No./Substance:
0/Antigen-Antibody Complex

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