| Variation in Growth of Infants with a Single Ventricle. | |
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MedLine Citation:
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PMID: 22336578 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: The study goal was to evaluate interstage growth variation among sites participating in the National Pediatric Cardiology Quality Improvement Collaborative registry caring for infants with hypoplastic left heart syndrome and to identify nutritional practices common among sites achieving best growth outcomes. STUDY DESIGN: This was a retrospective analysis of infants in the registry who had presented due to their superior cavopulmonary connection (SCPC) and whose surgical site had enrolled ≥4 eligible patients in the registry. The primary outcome variable was weight-for-age z-score (WAZ) change between Norwood discharge and presentation for SCPC (interstage period). Blinded, structured interviews were performed with each site regarding site-specific nutritional practices. Practices common among sites with positive interstage WAZ changes were identified. RESULTS: Sixteen centers enrolled 132 infants from December 2008 through December 2010. Median age at SCPC was 5 months (2.6-12.6), and median interstage WAZ change was -0.29 (-3.2 to 2.3). Significant variation in WAZ changes among sites was demonstrated (P < .001). Sites that used standard feeding evaluation prior to Norwood discharge and that closely monitored for specific weight gain/loss red flags in the interstage period demonstrated significantly better patient growth than those that did not use these practices (P = .002). CONCLUSIONS: Considerable variation exists in interstage growth among patients receiving care at these 16 surgical sites. Standardization of interstage nutritional management with focus on best nutritional practices may lead to improved growth in this high-risk population of infants. |
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Authors:
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Jeffrey B Anderson; Srikant B Iyer; David N Schidlow; Richard Williams; Kartik Varadarajan; Megan Horsley; Julie Slicker; Jesse Pratt; Eileen King; Carole Lannon; |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-14 |
Journal Detail:
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Title: The Journal of pediatrics Volume: - ISSN: 1097-6833 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Mosby, Inc. All rights reserved. |
Affiliation:
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The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; The James M. Anderson Center for Clinical Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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