| Variant angina pectoris: investigation of indexes of sympathetic nervous system function. | |
| | |
MedLine Citation:
|
PMID: 108989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
One thousand forty-five spontaneous episodes of S-T segment elevation were observed in three patients over a total of 72 days of continuous electrocardiographic monitoring. Eighty-nine percent of episodes were asymptomatic; chest pain tended to occur with episodes longer than 3 minutes, and ventricular ectopy occurred almost exclusively with symptomatic episodes. Nitroglycerin regularly relieved angina or S-T elevation, or both. Plasma and urinary catecholamines and their metabolites were normal. Episodes of variant angina were not associated with a generalized increase in sympathetic outflow because serum catecholamine levels at the onset and termination of the S-T abnormalities were not elevated. Controlled trials of propranolol showed no significant beneficial effect. Propranolol significantly increased the length of episodes of S-T elevation in one patient, increasing ventricular irritability. The overall course of variant angina was quite variable, with spontaneous and long-lasting remissions, necessitating cautions interpretation of clinical trials. |
| | |
Authors:
|
D Robertson; R M Robertson; A S Nies; J A Oates; G C Friesinger |
Related Documents
:
|
11775629 - Giant hiatal hernia presenting with stable angina pectoris and syncope--a case report. 15378129 - Current medical management of chronic stable angina. 8059719 - Tissue-type plasminogen activator and plasminogen activator inhibitor activities as pre... 11425769 - Biological profiles in subjects with recurrent acute coronary events compared with subj... 16111669 - Adiponectin serum concentrations in men with coronary artery disease: the ludwigshafen ... 3092969 - Course of angina pectoris after an acute coronary event. 10348119 - How good are experienced interventional cardiologists in predicting the risk and diffic... 15300869 - Ventricular myocardial thicknesses in anencephalic fetuses. 1746219 - Vertebral artery tortuosity with concomitant erosion of the foramen of the transverse p... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: The American journal of cardiology Volume: 43 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1979 Jun |
Date Detail:
|
Created Date: 1979-07-16 Completed Date: 1979-07-16 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1080-5 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Angina Pectoris
/
physiopathology* Angina Pectoris, Variant / drug therapy, physiopathology* Blood Pressure Carotid Sinus / physiopathology Catecholamines / blood, urine Cold Temperature Drinking Electrocardiography Exercise Test Humans Hydroxyindoleacetic Acid / urine Isometric Contraction Monitoring, Physiologic Nitroglycerin / therapeutic use Propranolol / therapeutic use Rectum / physiopathology Sympathetic Nervous System / physiopathology* Valsalva Maneuver Veins / physiopathology |
| Chemical | |
Reg. No./Substance:
|
0/Catecholamines; 525-66-6/Propranolol; 54-16-0/Hydroxyindoleacetic Acid; 55-63-0/Nitroglycerin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Need for chest radiographs during and after lymphography.
Next Document: Utilization of D-methionine during total parenteral nutrition in postsurgical patients.