Document Detail


Variable resolution electromagnetic tomography (VARETA) in evaluation of compression of cerebral arteries due to deep midline brain lesions.
MedLine Citation:
PMID:  15163464     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Hemispheric tumors produced electroencephalographic (EEG) delta activity mainly due to deafferentation of cerebral cortex. In small, deep midline lesions that compressed cerebral arteries, the most important abnormality should have been in EEG theta band that selectively responded to brain ischemia. Frequency domain-variable resolution electromagnetic tomography (FD-VARETA) has been applied satisfactorily to the study of brain tumors, cerebral infarcts, and brain hemorrhages and was shown to localize areas of hypoperfusion. METHODS: Twelve patients with deep midline lesions compressing different cerebral arteries were studied. Computer tomography (CT) and/or magnetic resonance imaging (MRI) as well as quantitative EEG with source calculation in frequency domain were obtained. Brain electromagnetic tomographies (BETs) were calculated to evaluate localization and extension of functional abnormalities. RESULTS: Ten of twelve cases presented abnormal sources in theta band as main abnormal source. In only two cases was the main source in delta band, but these cases also had abnormal Z values in theta band. In four patients there were only abnormal values in theta range. Sources of abnormal theta activity were observed in regions irrigated by the arteries compressed. CONCLUSIONS: In deep midline lesions, compression of cerebral arteries producing relative ischemia may explain abnormal EEG sources in theta band. Patients with main source in theta band showed vascular compression and some patients exhibited vasogenic edema. Thus, theta might be due to relative ischemia produced by both hypoperfusion and edema. Once again, VARETA has found to be very useful in evaluation of functional abnormalities.
Authors:
Antonio Fernández-Bouzas; Thalía Harmony; Thalía Fernández; Josefina Ricardo-Garcell; Efraín Santiago
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of medical research     Volume:  35     ISSN:  0188-4409     ISO Abbreviation:  Arch. Med. Res.     Publication Date:    2004 May-Jun
Date Detail:
Created Date:  2004-05-27     Completed Date:  2004-07-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9312706     Medline TA:  Arch Med Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  225-30     Citation Subset:  IM    
Affiliation:
Laboratorio de Psicofisiología, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus UNAM-UAQ, Juriquilla, Querétaro, Mexico. fabouzas@servidor.unam.mx
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain Neoplasms / pathology*
Cerebral Arteries / pathology*
Cerebral Cortex / pathology*
Electroencephalography / methods
Female
Humans
Magnetic Resonance Imaging / methods
Male
Middle Aged
Perfusion
Tomography / methods*
Tomography, X-Ray Computed / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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