| Variable flip angle-based fast three-dimensional T(1) mapping for delayed gadolinium-enhanced MRI of cartilage of the knee: Need for B(1) correction. | |
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MedLine Citation:
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PMID: 21120988 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Delayed gadolinium-enhanced MRI of cartilage is a technique, which involves T(1) mapping to identify changes in the structural integrity of cartilage associated with osteoarthritis. Currently, the gold standard is 2D inversion recovery turbo spin echo, which suffers from long acquisition times and limited coverage. Three-dimensional variable flip angle (VFA) is an alternate technique, which has been shown to be accurate when an estimate of T(1) is available a priori. This study validates the variable flip angle method for delayed gadolinium-enhanced MRI of cartilage of the femoro-tibial knee cartilage. When amplitude of (excitation) radiofrequency field inhomogeneities were minimized using nonselective pulses and amplitude of (excitation) radiofrequency field correction using an additional acquisition of a amplitude of (excitation) radiofrequency field map, the accuracy of T(1) measurements were improved, and slice-to-slice variations over the 3D volume were minimized. In conclusion, fast 3D T(1) mapping using the variable flip angle method with amplitude of (excitation) radiofrequency field correction appears to be an efficient and accurate method for delayed gadolinium-enhanced MRI of cartilage of the knee. Magn Reson Med, 2010. © 2010 Wiley-Liss, Inc. |
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Authors:
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Angela Manuel; Wei Li; Vladimir Jellus; Timothy Hughes; Pottumarthi V Prasad |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2010-11-30 |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: - ISSN: 1522-2594 ISO Abbreviation: - Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-12-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Radiology, Center for Advanced Imaging, NorthShore University HealthSystem, Evanston, Illinois, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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