| Variable ECG signs of ischemia during controlled occlusion of the left and right coronary artery in humans. | |
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MedLine Citation:
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PMID: 16428337 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Infarct size (IS) increases with vascular occlusion time, area at risk for infarction, lack of collateral supply, absence of preconditioning, and myocardial demand for O2 supply. ECG S-T segment elevation is used as a measure of severity of ischemia and a surrogate for IS. This study in 50 patients with coronary artery disease undergoing a first 120-s balloon occlusion of a stenosis sought to determine whether S-T segment elevation, corrected for the above-mentioned variables, in the left coronary artery (LCA group, n = 36) is different from that in the right coronary artery (RCA group, n = 14) territory. After consideration of all known determinants of IS, particularly mass at risk and collateral supply, the LCA territory is more sensitive than the RCA region to a 2-min period of myocardial ischemia. |
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Authors:
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Stefano F De Marchi; Pascal Meier; Philipp Oswald; Christian Seiler |
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Publication Detail:
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Type: Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't Date: 2006-01-20 |
Journal Detail:
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Title: American journal of physiology. Heart and circulatory physiology Volume: 291 ISSN: 0363-6135 ISO Abbreviation: Am. J. Physiol. Heart Circ. Physiol. Publication Date: 2006 Jul |
Date Detail:
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Created Date: 2006-06-14 Completed Date: 2006-08-01 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100901228 Medline TA: Am J Physiol Heart Circ Physiol Country: United States |
Other Details:
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Languages: eng Pagination: H351-6 Citation Subset: IM |
Affiliation:
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Department of Cardiology, University Hospital, Bern, Switzerland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Coronary Artery Disease
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classification,
complications,
diagnosis*,
physiopathology* Coronary Vessels / physiopathology* Electrocardiography / methods* Female Humans Ischemic Preconditioning / methods* Male Middle Aged Myocardial Ischemia / classification, diagnosis*, etiology, physiopathology* Reproducibility of Results Sensitivity and Specificity Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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