Document Detail

Variability in intraosseous pressure induced by saline flush of an intraosseous cannula by multiple practitioners.
MedLine Citation:
PMID:  22821045     Owner:  NLM     Status:  MEDLINE    
Intraosseous cannulation is an accepted means to achieve vascular access when peripheral venous access is not available. It is common practice to flush the intraosseous cannula with saline prior to establishing infusions. The objective of this study was to evaluate changes in intraosseous pressure during the flush procedure and to assess the variability of pressure changes induced by different practitioners. Two intraosseous cannulas were placed in an isolated cadaveric femur collected from a swine. Intraosseous pressure and the rate of change in pressure were recorded continuously during a series of saline flushes into a distal femoral intraosseous cannula by 21 members of the veterinary research staff at the authors' institution. Median peak intraosseous pressures exceeded 600 mmHg, and an inverse relationship was noted between peak intraosseous pressure and the duration of flush. Bone marrow fat emboli were grossly evident in flush effluents and their presence was confirmed by microscopic examination. Until the practitioners were informed of the pressure changes induced by the intraosseous cannula flush, few had appreciated the magnitude of the pressures that they had generated, suggesting that an instrumented intraosseous flush preparation like the one used in this study may prove useful as a training tool for flush procedures.
Bernard J Rubal; Kathleen McKay; Kevin R Armstrong; Mark P Rubal; Melissa J Marbach
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-07-20
Journal Detail:
Title:  Lab animal     Volume:  41     ISSN:  1548-4475     ISO Abbreviation:  Lab Anim (NY)     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-07-23     Completed Date:  2012-11-20     Revised Date:  2012-12-14    
Medline Journal Info:
Nlm Unique ID:  0417737     Medline TA:  Lab Anim (NY)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  224-9     Citation Subset:  IM    
Brooke Army Medical Center, Fort Sam Houston, San Antonio, TX, USA.
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MeSH Terms
Animal Experimentation*
Embolism, Fat / complications
Infusions, Intraosseous / adverse effects,  standards*
Pressure / adverse effects*
Research Personnel / education
Sodium Chloride / administration & dosage*
Wounds and Injuries / complications
Reg. No./Substance:
7647-14-5/Sodium Chloride
Erratum In:
Lab Anim (NY). 2012 Nov;41(11):349

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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