| Variability of QT dispersion measurements in the surface electrocardiogram in patients with acute myocardial infarction and in normal subjects. | |
| | |
MedLine Citation:
|
PMID: 7977069 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
QT dispersion (defined as maximal QT interval minus minimal QT interval) as assessed on the surface electrocardiogram has been demonstrated to reflect regional inhomogeneity of ventricular repolarization. However, the variability of repeated QT dispersion measurements has not been validated in a prospective study. Thus, the present study is based on the analysis of standard 12-lead surface electrocardiographic (ECG) tracings obtained in 127 persons including 50 subjects without structural heart disease and 77 patients presenting with acute myocardial infarction. RR and QT intervals were measured by means of a digitizer tablet and QT/QTc dispersion was subsequently calculated automatically by PC-based analysis software. Measurements were obtained on 2 separate occasions by the same observer to assess the intraobserver variability. In addition, all tracings were evaluated by a second investigator to determine the interobserver variability. QT dispersion in persons without heart disease averaged 30 +/- 10 ms compared with 56 +/- 24 ms in patients with acute myocardial infarction (p < 0.0001). Patients with infarction who developed ventricular fibrillation within the first 24 hours after admission (11 of 77) had an even larger QT dispersion of 88 +/- 30 ms (p < 0.0001). Repeated measurements of QT dispersion in all 127 subjects revealed a correlation coefficient of 0.91 for both intra- and interobserver variability. Similar results were obtained for repeated determination of QTc dispersion (r = 0.93 and r = 0.90, respectively). When only patients with infarction were considered, correlation coefficients between 0.84 and 0.88 were obtained.(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
A van de Loo; W Arendts; S H Hohnloser |
Related Documents
:
|
18433709 - Effects of pink grapefruit juice on qt variability in patients with dilated or hyperten... 6491039 - Recurrent torsade de pointes type ventricular tachycardia in intracranial hemorrhage. 12604879 - Ventricular tachyarrhythmias in a canine model of lqt3: arrhythmogenic effects of sympa... 11455519 - Electrophysiological characteristic of a patient exhibiting the short-coupled variant o... 18006439 - Spatial heterogeneity of myocardial perfusion predicts local potassium channel expressi... 19026859 - Long qt syndrome and short qt syndrome. 6350399 - Role of cellular proteinases in acute myocardial infarction. i. proteolysis in nonische... 8889359 - Hirulog: a direct thrombin inhibitor for management of acute coronary syndromes. 16351899 - The parasympathetic nervous system and its influence on heart rate in torpid western py... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The American journal of cardiology Volume: 74 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1994 Dec |
Date Detail:
|
Created Date: 1994-12-20 Completed Date: 1994-12-20 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1113-8 Citation Subset: AIM; IM |
Affiliation:
|
Department of Cardiology, University Hospital, Freiburg, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Electrocardiography* Female Humans Male Middle Aged Myocardial Infarction / physiopathology* Observer Variation Prospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Indications for low-density lipoprotein apheresis.
Next Document: Electrophysiologic effects of sotalol and amiodarone in patients with sustained monomorphic ventricu...