Document Detail


Varenicline for smoking cessation: efficacy, safety, and treatment recommendations.
MedLine Citation:
PMID:  21049087     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Smoking is the leading preventable cause of morbidity and mortality in the US, and decreasing smoking prevalence is a public health priority. Patients achieve the greatest success when quit attempts involve behavioral therapy combined with pharmacotherapy. Varenicline is the most recent addition to the pharmacotherapeutic armamentarium for the treatment of tobacco dependence. Varenicline is efficacious and cost-effective. Smoking relapse and adverse treatment-related side effects may decrease medication adherence and patient satisfaction with varenicline. In the clinical setting, varenicline treatment can be optimized by reducing doses in patients who experience intolerable side effects, increasing the dose in partial responders, and providing long-term maintenance therapy for relapse prevention.
Authors:
Jon O Ebbert; Kirk D Wyatt; J Taylor Hays; Eric W Klee; Richard D Hurt
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Publication Detail:
Type:  Journal Article     Date:  2010-10-05
Journal Detail:
Title:  Patient preference and adherence     Volume:  4     ISSN:  1177-889X     ISO Abbreviation:  Patient Prefer Adherence     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-04     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101475748     Medline TA:  Patient Prefer Adherence     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  355-62     Citation Subset:  -    
Affiliation:
Mayo Clinic College of Medicine, Rochester, MN, USA.
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