Document Detail

Vardenafil-induced generalized urticaria.
MedLine Citation:
PMID:  15482393     Owner:  NLM     Status:  MEDLINE    
Vardenafil is a potent selective and reversible inhibitor of the cGMP phosphodiesterase type 5 that has been shown to improve erectile function in men. Vardenafil is usually well tolerated; the most common adverse events are headache, flushing, rhinitis, sinusitis and dyspepsia. We report a case of a 48-year-old man with an acute episode of widespread urticaria following vardenafil consumption and in absence of other identifiable causative factors. The patient had no previous episodes of urticaria. This appears to be the first report of urticaria associated with vardenafil.
P L Minciullo; A Saija; M Patafi; L Giannetto; G Marotta; B Ferlazzo; S Gangemi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical pharmacy and therapeutics     Volume:  29     ISSN:  0269-4727     ISO Abbreviation:  J Clin Pharm Ther     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-10-14     Completed Date:  2005-01-14     Revised Date:  2008-05-28    
Medline Journal Info:
Nlm Unique ID:  8704308     Medline TA:  J Clin Pharm Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  483-4     Citation Subset:  IM    
Department of Human Pathology, Division and School of Allergy and Clinical Immunology, University of Messina, Italy.
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MeSH Terms
Erectile Dysfunction / drug therapy
Imidazoles / adverse effects*,  therapeutic use
Middle Aged
Phosphodiesterase Inhibitors / adverse effects*,  therapeutic use
Piperazines / adverse effects*,  therapeutic use
Urticaria / chemically induced*
Reg. No./Substance:
0/Imidazoles; 0/Phosphodiesterase Inhibitors; 0/Piperazines; 0/Sulfones; 0/Triazines; 224785-90-4/vardenafil

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